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This is a very interesting video because it shows what happens when the left cortex is inhibited,specifically the speech areas. The person has difficulty speaking but when asked to sing has no problem. The right hemisphere kicks in and can sing the words. This can be used as a teaching aid for children with learning disabilities or for stroke patients. If any one saw the movie The Kings Speech this was one of the therapists tricks to helping him stop his stuttering. As for TMS or tDCS they need to study the after effect and make sure there is no long term damage. TMS has been around for over 15 years but I haven't seen any long term studies of patients who have been treated with it. Mcnamara chiropractic, Mcnamara, Dr Joe McNamara,drjoemcnamara, Joe McNamara, cumming chiropractic, cumming functional neurologist, south forsyth functional neurologist, forsyth functional neurologist, johns creek functional neurologist, atlanta functional neurologist, johns creek chiropractic, south forsyth chiropractic, forsyth chiropractic, functional neurology, functional neurologist,

Research

Further characterization of autoantibodies to GABAergic neurons in the central nervous system produced by a subset of children with autism

Sharifia Wills, Christy C Rossi, Jeff Bennett, Veronica Martinez-Cerdeno, Paul Ashwood, David G. Amaral and Judy Van de Water

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Molecular Autism 2011, 2:5 doi:10.1186/2040-2392-2-5

Published: 26 April 2011

Abstract (provisional)

Background

Autism is a neurodevelopmental disorder characterized by impairments in social interaction, deficits in verbal and nonverbal communication, with the presence of repetitive behaviors or a limited repertoire of activities and interests. The causes for autism are currently unclear. In a previous study, we determined that 21% of children with autism had plasma autoantibodies that were immunoreactive with a population of neurons in the cerebellum that appeared to be Golgi cells, a GABAergic interneuron.

Methods

We have now extended this analysis by examining plasma immunoreactivity in the remainder of the brain. To determine cell specificity, double labeling studies, that included one of the calcium binding proteins that are commonly co-localized in GABAergic neurons (calbindin, paralbumin, or calretinin), were also carried out to determine which GABAergic neurons were immunoreactive. Coronal sections through the rostrocaudal extent of the macaque monkey brain were reacted with plasma from each of seven subjects with autism who had previously demonstrated positive Golgi cell staining, as well as six negative controls. In addition, brain sections from murine adult males were similarly examined.

Results

In each case, specific staining was observed for neurons that had the morphological appearance of interneurons. By double labeling sections with plasma and with antibodies directed against gamma-aminobutyric acid (GABA), we determined that all autoantibody-positive neurons were GABAergic. However, not all GABAergic neurons were autoantibody-positive. Calbindin was co-labeled in several of the autoantibody labeled cells while parvalbumin co-labeling was less frequently observed. Autoantibody-positive cells rarely expressed calretinin. Sections from the mouse brain processed similarly to the primate sections also demonstrated immunoreactivity to interneurons distributed throughout the neocortex and many subcortical regions. Some cell populations stained in the primate (such as the Golgi neurons in the cerebellum) were not as robustly immunoreactive in the mouse brain.

Conclusions

These results suggest that the earlier report of autoantibody immunoreactivity to specific cells in the cerebellum extend to other regions of the brain. Further, these findings confirm the autoantibody-targeted cells to be a sub-population of GABAergic interneurons. The potential impact of these autoantibodies on GABAergic disruption with respect to the etiology of autism is discussed herein.

The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.

This may explain why certain babies develop autism after being vaccinated. The vaccinating process introduces foreign particles into a babies blood stream which causes an immune reaction. In embryology we were taught that a babies immune system doesn't start to function properly on it's own until it's over 1 year old. Introducing many foreign bodies into a newborns system via multiple vaccinations may actually cause the babies developing immune system to crash. This could cause massive inflammation through out the body and also cause the babies immune system to attack its own cells(brain). This is an area that has been over looked but needs to be further investigated. McNamara Chiropractic, Cumming chiropractic,johns creek chiropractic, south forsyth chiropractic, forsyth chiropractic, functional neurology, atlanta functional neurology, forsyth functional neurology, south forsyth functional neurology, johns creek functional neurology, cumming neurology, cumming neurologist, functional neurology, functional neurologist, neuroscience, neurology

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I have told many of my patients,friends and family to be very careful and aware of how they use their cell phones. Some think I'm crazy but I have good reason. I have had 3 patients in their early 40's die from Glioblastoma's. This use to be a very rare brain tumor but in the last 10 years has increased significantly. Having just one patient with a Glioblastoma not to mention 3 come into my office, in my life time, should be an extremely rare occurrence. Please use speaker phone and don't let your kids use a cell phone unless it's on speaker phone. McNamara Chiropractic, McNamara, Dr Joe McNamara, drjoemcnamara, functional neurologist, atlanta functional neurology, cumming functional neurologist, Johns creek functional neurologist, forsyth functional neurologist, south forsyth functional neurologist, johns creek chiropractic, south forsyth chiropractic, cumming chiropractic, forsyth chiropractic, neuroscience, neurology

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